Japaneses Society of Internal Medicine Symposium 2007 105-106 Jp/imindex.html

Following its establishment in childhood, Helicobacter pylori causes chronic inflammatory changes in the gastric mucosa, which leads to gastric ulcers, cancer, and mucosa-associated lymphoid tissue lymphoma (MALToma) in the stomach. In addition to various gastric diseases, H pylori infection is reported to be related to various extragastric diseases, such as idiopathic thrombocytopenic purpura (ITP) and dermatitis. Further, the infection rate has been shown to be higher in patients with lifestyle-related ischemic heart and cerebrovascular diseases than in controls, and was suggested to be related to their development. Since those lifestyle-related diseases are caused by arteriosclerosis, there is significant interest in the relationship between arteriosclerosis and H pylori infection.(Click here to view/order article at Pubmed)