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Relation of IgG and IgE Levels to Allergens
Dr. Lynn Averill, MD, PhD
Eysink PE, De Jong MH, Bindels PJ, Scharp-Van Der Linden VT, De Groot CJ, Stapel SO, Aalberse RC. Relation between IgG antibodies to foods and IgE antibodies to milk, egg, cat, dog and/or mite in a cross-sectional study. Clin Exp Allergy. 1999 May;29(5):604-10. (Click here to view/order article at Pubmed) Dr. Averill:
Patients with increased IgG antibody to egg white, orange, and mixture of wheat and rice should have IgE levels tested to cat, dog, mite, egg, milk, as well as, to inhalant allergens
An increased IgG antibody level to foods especially to egg white, orange, and mixture of wheat and rice indicates an increased risk of having IgE to cat, dog, mite, egg, and/ or milk allergens.
IgE to egg and milk are closely associated with the development of IgE to inhalant allergens.
Food sensitization is associated with an increased future risk for sensitization to inhalant allergens. IgG might be useful in determining a child's risk of becoming allergic within a few years and therefore could be used as an early marker for the development of IgE-mediated allergy.
Various environmental factors have been thought to influence the development of both IgE antibodies and allergic disease. Exposure to inhaled allergen is important, but other environmental factors are also of influence such as passive smoking, diet of mother and child perinatal, pets, number of siblings, breast feeding, and month of birth.Dr. Bennett:
Rationale for using IgG food allergy testing as a predictor for future risk of IgE allergies, food and airborne.Dr. Constantine
Higher IgG levels in children often correlate with higher IgE levels to cat, dog, mite, egg, and / or dairy. Thus, early detection of IgG reactions may help prevent IgE development.
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